Advanced 3D cell models recreate the complexity of human tissues, enabling researchers to examine tumor progression, probe neurological disorders, and assess therapeutic candidates. By capturing the ...

New research tracks how cells prepare gene regulatory decisions that will define their fate during the earliest stages of ...

Many promising therapies fail because preclinical models do not fully capture the complexity of the human heart. A new review ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

Cambridge scientists have grown miniature circuits in the lab that mimic how the brain and spinal cord connect, which underlies human movement. They used this model to show how damage to these ...

Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

Summary: A milestone neuro-regenerative study has shattered a long-standing medical dogma by proving that “irreversible” damage to the connections between the human brain and spinal cord can be ...

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...