Au8, an experimental ALS therapy. CNM-Au8 has been associated with NfL reductions, a biomarker finding linked to longer ...

Two different potential biomarkers for amyotrophic lateral sclerosis (ALS) have been identified, which it's hoped will help stratify patients and guide clinical trials of new therapies. One biomarker ...

SALT LAKE CITY, Dec. 03, 2025 (GLOBE NEWSWIRE) -- Clene Inc. (Nasdaq: CLNN) (along with its subsidiaries, “Clene” or the “Company”) and its wholly owned subsidiary Clene Nanomedicine, Inc., a late ...

FDA stated that the “proposed data may be capable of supporting the submission and review of an [NDA] under the accelerated approval pathway” for ...

The agency said NfL could be used as a marker to predict patient benefit, but more data is still needed to confirm that link.

The data cover the first part of an ongoing Phase 1/2 clinical trial (NCT06556394), in which participants received a single injection of RAG-17 at doses ranging from 30-180 mg, or ...

NORTH BRUNSWICK, N.J.--(BUSINESS WIRE)--LinusBio, a leader in exposomic sequencing and precision health, today announced the publication of a study in The Lancet’s eBioMedicine that demonstrates a ...

UTRECHT, Netherlands & AMSTERDAM--(BUSINESS WIRE)--UMC Utrecht has enrolled its first patient for a new study to identify biomarkers of Amyotrophic Lateral Sclerosis (ALS). The observational ...

12-month data demonstrated regulation of iron levels, which aligns with improved ALS survival and disease mitigation Previous results showed PrimeC slowed disease progression by 36% and improved ...

The FDA has granted an in-person Type C meeting during the first quarter of 2026 New independent analyses across large observational ALS cohorts demonstrate that modest (~10%) NfL reductions are ...

Researchers have reported major advances in understanding and treating ALS and Parkinson’s disease, with potential to reshape ...

A new study may finally change how amyotrophic lateral sclerosis (ALS) is diagnosed. Scientists from UCLA Health and the University of Queensland developed a blood test that can spot signs of the ...