The authors found that Csk (a tyrosine kinase that attenuates B cell receptor signaling) is required for germinal center maintenance and efficient antibody maturation. Osaka, Japan – The immune system ...

A simulation of a broadly neutralizing antibody (dark and light blue chains) binding to the HIV-1 viral membrane. The membrane comprises lipids and cholesterol (gray sticks) and phosphates (orange ...

A detailed analysis of T-cell redirecting therapies in oncology, comparing the mechanisms of bispecific antibodies and CAR T cells.

Insurance Disparity in Novel Hormonal Therapy Initiation in Patients With Metastatic Hormone-Sensitive Prostate Cancer: Medicare Advantage Versus Traditional Medicare Regulatory approval of B-cell ...

In many fields of endeavor, traditional techniques are being turbocharged by rapid, rational, computer-driven techniques—that is, by artificial intelligence (AI). And there is plenty of evidence that ...

A panelist discusses early clinical trial data on combining the B-cell maturation antigen–targeting bispecific antibody linvoseltamab with proteasome inhibitors carfilzomib and bortezomib in ...

Accelerate your therapeutic antibody programs, from early concept to IND submission, with Pharmaron’s fully integrated discovery and development services. The platform supports monoclonal, bi-specific ...

Using real-world data, researchers compared 2 chimeric antigen receptor (CAR) T-cell therapies with a bispecific antibody, teclistamab, in multiple myeloma (MM). Treatment options for patients with ...