Artificial antigen-presenting cells (aAPCs) are engineered constructs designed to emulate the functions of professional antigen-presenting cells. By displaying tumour-associated peptide–MHC complexes ...

To move forward or migrate, the different cells in our body must exert forces or interact with their surrounding environment. Interestingly, however, a fault in these interactions can also be the ...

Cancer immunotherapy works by mobilizing the body's own immune system to recognize and destroy malignant cells.

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

Professional antigen-presenting cells—monocytes and macrophages—engulf these proteins, digest them into short peptide ...

MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious ...

Antigen-presenting cells activate invariant natural killer T (iNKT) cells, and this combination with α-galactosylceramide subsequently activates the body’s own T cells to fight tumors. This image was ...

New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...

The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes that have the potential to induce adaptive immune responses for food allergies. Upon genetic ...

A decade ago, a clinical trial in the U.K. notably showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children ...