An unusual protein structure known as a "rippled beta sheet," first predicted in 1953, has now been created in the laboratory and characterized in detail using x-ray crystallography. The new findings, ...

An unusual protein structure known as a “rippled beta sheet,” first predicted in 1953, has now been created in the laboratory and characterized in detail using x-ray crystallography. The new findings, ...

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's. Despite its constant stint in the limelight, however, researchers ...

The rippled sheet is a distinctive variation on the pleated beta sheet, which is a well-known structural motif found in thousands of proteins, including important disease-related proteins. Linus ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. But in some people, immune cells called microglia break down these proteins before they can ...