A major obstacle is the blood-brain barrier, which Kunwar described as similar to “Saran Wrap” surrounding every blood vessel in the brain. This barrier evolved to protect the brain from foreign ...
Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from passing ...
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Boosting the blood-brain barrier could avert brain damage in athletes
The neurodegenerative condition chronic traumatic encephalopathy appears to be driven by damage to the blood-brain barrier ...
The FDA has granted orphan drug designation (ODD) to a locally delivered formulation of irinotecan (ChemoSeed) for the ...
Peptide conjugation techniques are advancing CNS delivery of oligonucleotides, addressing blood-brain barrier challenges and ...
The blood–brain barrier functions as an evolutionarily optimized vascular “filter,” permitting limited penetration of small ...
Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...
Our brain is a fortress. Its delicate interior is completely surrounded by a protective wall called the blood-brain barrier. True to its name, the barrier separates contents in the blood and the brain ...
Vect-Horus has a clinical-phase solution to a key drug development challenge: crossing the blood–brain barrier (BBB). By targeting receptors on the barrier, Vect-Horus is empowering partners such as ...
New research reveals how a "leaky" blood-brain barrier connects sports-related head injuries to long-term brain disease like CTE.
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