A new study from Yale School of Medicine has shown that the neurons that generate higher cognition, and are a target of pathology in Alzheimer's disease and mental disorders such as schizophrenia, ...

Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

SPG601 is an investigational small molecule large-conductance, calcium-activated potassium channel activator. The Food and Drug Administration (FDA) has granted Fast Track designation to SPG601 for ...

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex Phillippidis, ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...