Medications are designed to treat diseased tissues while sparing healthy ones, often by attaching the drug to something that ...
Positive Phase 1 data confirm MP0317’s tumor-localized CD40 activation with a favorable safety profile in patients with advanced cancer ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...
Pancreatic cancer has long been oncology’s most stubborn adversary. Fewer than 13% of patients survive five years after ...
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film. By selecting which scenes to keep and which to leave out, ...
Comprehensive genomic profiling of matched ctDNA and tissue from patients with less common cancers enrolled in but not eligible for a treatment arm of the NCI-MATCH trial. Circulating tumor DNA (ctDNA ...
AI-driven genomic analysis could help researchers identify existing drugs that may be repurposed for subtype-specific breast ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...
A new stem-cell-derived model suggests human pancreatic cells require multiple genetic failures before becoming cancerous and ...
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...