tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...