How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Sculpture of the DNA helix outside the Francis Crick Centre. Image by Tim Sandle. For more than half a century, protein crystallization has been one of the great bottlenecks of structural biology.

Scientists at Durham University, working in partnership with Jagiellonian University in Poland, have developed a new nanoscale tool that can capture and precisely position some of the most important ...

A genome search and protein language model produced new DNA-moving proteins, including one that doubled targeted insertion in lab tests.

Generative AI is biology’s new playground. The technology powering popular chatbots can also dream up new, entirely novel versions of life’s most basic molecules, from DNA to proteins. Once the domain ...

Data from a new study in mice connects unrepaired DNA-protein crosslinks (DPCs), highly toxic tangles of protein and DNA, to inflammation-linked premature aging and embryonic lethality in mice. The ...

A new engineered gene-editing system, proven in bacteria and showing promise for use in plants, animals and humans, addresses ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...