LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.

In a recent study published in the journal Cell, researchers identify lipidomes as four cluster of differentiation 1 (CD1) antigen-presenting molecules and, as a result, reveal a map of self-lipid ...

Engineers have developed an automated microfluidic platform that dramatically accelerates the formulation of lipid nanoparticles, the delivery vehicles behind mRNA vaccines and gene therapies.

AI has designed candidate drugs for antibiotic-resistant infections and genetic diseases. But efforts to incorporate AI into the design of lipid nanoparticles (LNPs), the revolutionary delivery ...