In this work, we explore a more atom-economic radical disulfuration strategy that operates without the need of a pre-functionalized radical precursor via direct C-H bond functionalization using a ...
A new wave of antibody-targeted anticancer therapies is showing great clinical promise, with the potential to transform cancer treatment. These antibody-drug conjugates (ADCs) are multicomponent ...
Next-generation site-specific cysteine-based antibody–drug-conjugates (ADCs) broaden therapeutic index by precise drug-antibody attachments. However, manufacturing such ADCs for clinical validation ...
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