A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...

The interplay between G protein-coupled receptors (GPCRs) and fatty acid metabolism is emerging as a pivotal aspect in the pathogenesis and treatment of type 2 diabetes. Receptors such as free fatty ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...

Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...

Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into ...

A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

Lefkowitz started to trace cell receptors in 1968. Using radioactivity, he managed to unveil several receptors, including one for adrenalin, the β-adrenergic receptor. His team then extracted the ...

Brian Kobilka will visit the Department of Chemistry to give his Frontiers in Chemistry Lecture as a Shaomeng Wang and Ju-Yun Li Distinguished Lecturer. The event will take place Thursday, Feb. 29, at ...

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...