The resistance of tumours to immune-mediated lysis has been linked to the biology of matrix metalloproteinases (MMPs), and specifically to the cell surface expression of MMPs by the tumour cell. The ...
β-Secretase (BACE, Asp-2) is a transmembrane aspartic proteinase responsible for cleaving the amyloid precursor protein (APP) to generate the soluble ectodomain ...
Southern corn leaf blight, caused by the maize pathogen Cochliobolus heterostrophus, is a major disease affecting maize-growing regions worldwide, posing a serious threat to national food security and ...
A research group led by Osaka University and collaborative institutions discovered that disorders in the same gene PIGG are the cause for intellectual disability with seizures and hypotonia. PIGG is ...
A recent study shows that the testicular angiotensin converting enzyme (ACE) has a new unexpected activity: it is responsible for cleaving GPI off from proteins anchored on the sperm cell membrane. In ...
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