The RFC1 G80A polymorphism is closely associated with higher rates of methotrexate-induced toxicity in pediatric acute lymphoblastic leukemia (ALL), according to a study published in the World Journal ...

Chronic hepatitis B (CHB) poses a major global health burden, with China particularly affected. Effective antiviral therapy is crucial to prevent disease progression, but responses may vary by ...

Converting next-generation sequencing (NGS) image files into a set of called SNPs involves a number of steps including image analysis, alignment and assembly, SNP calling and genotype calling.

Any organism is a by-product of both its genetic makeup and the environment. To understand this in detail, we must first appreciate some basic genetic vocabulary and concepts. Here, we provide ...

The characteristics of an organism emerge through complex interactions of its genetic make-up and the effects of the environment. This article discusses this terminological distinction in genetics - ...

Sexually transmitted ringworm, known as trichophyton mentagrophytes genotype VII, or TMVII, is a fungus that infects the skin.

In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in ...

Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma Patients with SAs had a mean increase of 120 ...

In phase 2 studies, treatment with the all-oral combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor ledipasvir resulted in high rates of sustained virologic response ...

The Focus on Sickle Cell Foundation (FoSCel) has called on Ghanaians to make genotype testing a priority before entering ...