Maintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose. For decades, treatments ...

Glucagon is a pancreatic hormone that plays a crucial role in regulating glucose and whole-body energy metabolism. In individuals with diabetes, the pancreatic alpha cells that produce glucagon are ...

New findings raise the possibility of promising therapeutic strategies for the management of hypoglycemia in type 1 diabetes patients. Study: Loss of electrical β-cell to δ-cell coupling underlies ...

Beta cells play a key role in the pathogenesis of both Type 1 and Type 2 diabetes. However, pancreatic islets also have alpha cells that produce the hormone glucagon, which acts to raise glucose blood ...

The US Food and Drug Administration (FDA) has approved a prefilled glucagon rescue pen (Gvoke HypoPen, Xeris Pharmaceuticals) for the treatment of severe hypoglycemia in adult and pediatric patients ...

A new study led by Ananda Basu, M.D., used novel non-radioactive, stable glucagon tracers for the first time to characterize glucagon metabolism in humans with and without Type 1 diabetes, providing ...

CHICAGO & DUBLIN--(BUSINESS WIRE)--Xeris Pharmaceuticals, Inc. (Nasdaq: XERS), a specialty pharmaceutical company leveraging its novel formulation technology platforms to develop and commercialize ...

A lab-designed protein mimicking both insulin and glucagon has shown promising results for controlling blood sugar in Type 1 diabetes The formulation may not require ...

IT has been shown in this and other laboratories that the administration of glucagon will produce an intense but temporary diabetes in force-fed rats and in human subjects. 1–3 However, a diabetes ...