The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

The miniature models could exponentially accelerate vaccine development, cancer treatment research, and improved health outcomes across a spectrum of diseases. The left image shows the immune organ-on ...

How does the same infection, say the flu or a cold, give some people mild symptoms and leave others suffering? Why do people develop autoimmune diseases? And will we ever be able to predict when—and ...

Ancient encounters between humans and the mysterious Denisovans are still shaping people today. By analyzing genomes from populations across the Pacific, researchers uncovered evidence that the ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells—by using engineered ...

In a recent review published in the European Journal of Immunology, a group of authors summarized current advances, challenges, and future directions in human systems immunology using multi-omics ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." The human immune system is a remarkable evolutionary tool that is often taken for granted—until, that is, ...

I am lying under a blanket, feeling rough, staring at a bowl of oranges. Every fibre of my being is urging me to devour the lot. I can hear my mum – and medical friends at university – insisting that ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...