Immune system disorders in children can involve an underactive, overactive, or misdirected immune response. Main groups include immunodeficiencies, autoimmune diseases, atopic diseases, and ...

Scientists have pinpointed genetic changes that can leave children born with little to no immune defence against infection. In a new study of 11 affected individuals, researchers from Newcastle ...

Genomic integrity in lymphocytes relies on precise repair of DNA double-strand breaks (DSBs) introduced during antigen-receptor gene assembly and by exogenous insults. The non-homologous end joining ...

Representing a group of over 450 rare inherited conditions, Primary Immunodeficiency Disorders (PIDs) are typically characterised by increased susceptibility to infections and dysregulation of the ...

Early results from a study of newborn screening methods show that DNA analysis picks up many more preventable or treatable serious health conditions than standard newborn screening and is favored by ...

Severe Combined Immunodeficiency (SCID) is the name for a group of inherited disorders that cause babies to be born without a working immune system. These disorders are also called primary immune ...

Researchers have identified the genetic basis behind certain severe immunodeficiencies in newborns, paving the way for potential screening and emerging therapies. The findings, published today (24 May ...

NAVI MUMBAI: A timely medical intervention in the form of a bone marrow transplant, medically known as hematopoietic stem cell transplantation (HSCT), proved to be a lifesaving treatment for a ...

Having primary immunodeficiency (PI) doesn't mean avoiding exercise. Learn how to build a flexible, infection-aware routine ...

Given the heterogeneity and rarity of inborn errors of immunity (IEIs), management guidelines that deal with primary immunodeficiency as a whole are rare. The most recent general guideline, the ...

Clinical services include treatments for allergies, asthma and respiratory issues, skin conditions, digestive disorders and immune system disorders. The division is also active in the community; team ...

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the ...