Researchers in Japan showed that a unique neutrophil subset, characterized by type II interferon signature genes (T2ISG), along with elevated levels of interferon gamma in the blood, can predict the ...

Objectives Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic autoimmune disease where infections ...

Avacopan was safe and effective among patients with respiratory tract manifestations of antineutrophil cytoplasmic antibody-associated vasculitis. Avacopan shows promising efficacy and safety among ...

Microscopic polyangiitis (mPA) is a systemic necrotizing nongranulomatous vasculitis that affects small blood vessels. Clinical features include constitutional symptoms such as fever, anorexia, ...

Please provide your email address to receive an email when new articles are posted on . Avacopan was associated with fewer serious adverse events than controls in ANCA-associated vasculitis. Data from ...

Rates of neutropenia, lymphopenia, and infections were lower in the patients receiving avacopan than those who were not. Avacopan has been found to be safer and to lead to fewer infections in patients ...