About 50% Of The Population Has This Gene Mutation — Why Creatine May Help

Creatine is best known for its role in muscle energy and exercise performance. But it also connects to the body’s methylation cycle and, potentially, common variants in the MTHFR gene. Roughly half of ...
Nature

Dynamic inter-domain transformations mediate the allosteric regulation of human 5, 10-methylenetetrahydrofolate reductase

S-adenosyl-L-methionine (SAM) is the most important methyl group donor of the cell. It facilitates over 200 transmethylation reactions that modify DNA, RNA, proteins, and metabolites 1. Indeed, SAM is ...
Nature

Association between methylenetetrahydrofolate reductase C677T polymorphisms and male oligozoospermia, asthenozoospermia or oligoasthenozoospermia: a case–control study

In recent years, the infertility rate has increased worldwide due to various harmful factors such as life pressure, environmental deterioration and food contamination. According to statistical data, ...