The RFC1 G80A polymorphism is closely associated with higher rates of methotrexate-induced toxicity in pediatric acute lymphoblastic leukemia (ALL), according to a study published in the World Journal ...
Patients with methotrexate-associated acute kidney injury (AKI) had better odds of kidney recovery when treated with glucarpidase (Voraxaze), researchers found. Treatment with glucarpidase was ...
Please provide your email address to receive an email when new articles are posted on . Patients who received glucarpidase for acute kidney injury from methotrexate treatment had improved kidney ...
Twenty doses of outpatient HD-MTX with glucarpidase were administered to seven patients. After 20 of 20 (100%) treatments, serum MTX levels were reduced to <100 nmol/L. Treatments were well-tolerated, ...
Prospective Evaluation of the Pathologic Diagnosis and Treatment Outcomes of Pediatric Burkitt Lymphoma in the Central American Pediatric Hematology-Oncology Association Consortium Infusions of ...
An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate (MTX), according to a new study by investigators ...
Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research published at the ATS 2025 International ...
Jylamvo is now approved for pediatric acute lymphoblastic leukemia and juvenile idiopathic arthritis, offering a liquid methotrexate formulation. The formulation is stable at room temperature for 90 ...
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