Why do some people develop cancer while others, exposed to seemingly similar environments and living comparable lifestyles, ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

Mutation rates govern the introduction of genetic variation and influence evolutionary trajectories, disease susceptibility and species diversity. Rates are shaped by a balance between DNA damage, ...

In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...

Every time a cell divides, its chromosomes must be distributed correctly between the two daughter cells. Central to this process is the centromere, a specialized region of the chromosome. The ...

This mutation rate dictates how quickly species can adapt to changing environments. Supported by a combined $2.08 million in total NSF funding across partner institutions, the multi-institutional ...

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

This retrospective, observational study included patients 18 years or older at ER+/HER2– metastatic breast cancer diagnosis who initiated first-line therapy with aromatase inhibitors (AI) or selective ...

Inheriting a mutation in BRCA1 or BRCA2 puts you at higher risk of breast, prostate, ovarian and pancreatic cancer. Genetic ...

A new study by scientists at City of Hope ® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals. Some study ...