Neuroblastoma can be a particularly insidious cancer. In about half of all cases, tumors regress, even without therapy. In the other half, tumors grow very quickly. These tumors often respond well to ...

Although hypomethylating agents are currently used to treat patients with cancer, whether they can also reactivate and up-regulate oncogenes is not well elucidated. By combining analysis of patient ...

How does a proto-oncogene cause cancer? In the early twentieth century, a tumor-causing virus called the Rous sarcoma virus (retrovirus) was discovered. 3 Host cell proto-oncogene (c-src) and Rous ...

Many people are familiar with oncogenes - genes long known to be involved in cancers in humans, such as the gene "Src." What's less widely understood is that oncogenes didn't evolve just to cause ...

Microscopic image showing parts of the HER2 receptor touching each other inside the cells (green) and outside the cells (red) in a process called dimerization. The lack of red shows that cells with ...

As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children's Hospital, published in Cell, finds that the brain's resident immune cells, ...