Macrophages are key components of the immune response. They are able to capture and degrade pathogens such as parasites or bacteria using several receptors that can be opsonic receptors such as those ...

A previously unidentified physically activated pathway for cellular uptake in the body’s immune defence system could predate commonly recognized receptor-mediated processes. The pathway relies on ...

Suppressing CD33 stimulates phagocytosis, slows plaque growth. A protective CD33 mutation could be a gain of function that activates phagocytosis. The CD33 receptor acts as a dimer. At the 14th ...

Microglia tend to get off-kilter in Alzheimer’s and other neurodegenerative diseases. Now, researchers in Tony Wyss-Coray’s lab at Stanford University believe they have discovered a means of restoring ...

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

The coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 4.9 million deaths worldwide, as well as a significant ...

IBEC’s Principal Investigator César Rodriguez-Emmenegger has been awarded an ERC Consolidator Grant to develop Phagocytic Synthetic Cells (PSCs) to fight antibiotic-resistant pathogens. César ...

As microbes invade the human body, phagocytic cells such as macrophages spring into action to clear the intruders. These cells extend arm-like projections and wrap them around the microbes before ...

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way and kill their prey with acid. However, ...

Phagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have ...