The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered, layered structure. Its proper development requires newly generated neurons to ...

A team of researchers has created the first 'multiome' atlas of brain cell development in the human cerebral cortex across six broad developmental time points from fetal development into adulthood, ...

Researchers found that nonsense-mediated mRNA decay, via the UPF2 protein, is crucial for neuronal migration and cortical ...

Researchers at the University of Seville have analyzed alterations in the cerebral cortex in people suffering from psychosis. Their findings show that psychosis does not follow a single trajectory, ...

Determining the genetic and epigenetic factors that influence brain folding is the objective of the latest study co-led by the Neurogenesis and Cortical Expansion laboratory, directed by researcher ...

Researchers discover that the RNA surveillance system NMD and the protein UPF2 are essential for guiding neuronal migration and forming the brain's layered cortex.

The human brain ages less than thought and in layers – at least in the area of the cerebral cortex responsible for the sense of touch. Researchers at DZNE, the University of Magdeburg, and the Hertie ...

A recent study published in Nature Communications demonstrated how droplet-based three-dimensional (3D) printing could help fabricate cerebral cortex tissues comprising layer-specific neurons ...

The microscopic image shows a nerve cell and a magnified view of the investigated synapses. Calcium was released at these sites using a UV flash, which triggered the release of the neurotransmitter.