This show marks the final Backlash for John Cena, who is calling it quits at the end of the year. He'll main event Backlash against a longtime rival.

"WWE Backlash 2025" commences this Saturday, which means it's time for predictions. Headlining the first PLE following "WrestleMania 41" will be an Undisputed WWE Championship match. Randy Orton has renewed his rivalry with John Cena in a bid to become a 15-time world champion.

It all comes down to where Backlash falls in WWE’s yearly calendar. Triple H, Bruce Prichard and the rest of the writers spend months setting up storylines and paying them off a

WWE Raw on May 5 delivered chaos with Penta’s victory, Rusev’s violent return, and IYO SKY getting ambushed ahead of Backlash 2025.

Jey @WWEUsos defends the World Heavyweight Championship for the very first time on #WWERaw against former champion @WWERollins! pic.twitter.com/GQQadCgp0Q— WWE (@WWE) May 6, 2025 May 6 (UPI) --World Heavyweight Champion Jey Uso defended his title against Seth Rollins in the main event of WWE Raw.

Seth Rollins' "vision" for the future of wrestling includes holding the world heavyweight championship. Rollins was moments away from seeing that come to fruition against Jey Uso on Monday's episode of Raw when Sami Zayn and CM Punk intervened to allow Uso to retain the title.