In plain language. Written by scientists. Scientists discovered that a specific type of brain cell becomes unusually quiet in Huntington’s disease. By restoring the activity of these cells in mice, ...

Its speech measures reflected clinical scores and HD-related changes over time, suggesting it could be used as a remote ...

Huntington’s disease (HD) is typically viewed as a brain disorder, but new research highlights its lesser-known effects on the body, especially on muscles, fat, and nutrition, even in the early stages ...

A review of 23 studies found that EEG changes were linked to disease progression and clinical measures in HD. While more research is needed, EEG holds potential to become a simple, non-invasive ...

In plain language. Written by scientists. New 12-month data from Skyhawk’s SKY-0515 is in and all four measures that make up the cUHDRS are at or above baseline, beating expected natural decline. Plus ...

On December 3, 2024 a study site gave word that the very first person received a new drug, called ALN-HTT02, as part of a ...

In plain language. Written by scientists. Getting “stuck” on a thought, action, or conversation can be a symptom of HD—not stubbornness. New research suggests perseveration may begin earlier than ...

You may have heard the saying, “you can’t run on empty.” A person living with HD may be eating regular meals, or even seem ...

In plain language. Written by scientists. A CRISPR-based approach called “base editing” is being explored to develop a new potential treatment for Huntington's disease. Editing a single letter in the ...

Vico Therapeutics’ Huntington’s disease drug VO659 is now being tested just twice a year, and the FDA has cleared the way for US trials to begin later this year. Like other ASOsASOs A type of gene ...

September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, ...

Huntington’s disease (HD) involves the loss of cells in the striatum, an area of the brain that plays important roles in movement, cognition, and behaviour. For decades, researchers have been ...