New DNA sequencing methods detect rare mutations acquired as bodies grow and age

Somatic mutations, the DNA changes that occur as our bodies grow and age, not only hold an important key to cancer but are ...

Random mutations turn RNA droplets into cell-like structures that move and store cargo

A small number of random genetic mutations cause simple RNA droplets to transform into cell-like structures. In this process, ...
CURE

Firmonertinib Shows Responses in Lung Cancer With EGFR PACC Mutations

Depending on dose, firmonertinib shrank tumors in 43% to 68% of patients as a first treatment for EGFR PACC-mutant lung ...
BIOENGINEER

Rare Gene Mutation Rewires Developmental Programs in Alazami Syndrome, Revealing Cardiac Risk

In a finding that could reshape how clinicians think about one of the rarest neurodevelopmental disorders on record, a team ...
BIOENGINEER

Shared STAT3 and TET2 Mutations Trace a Rare Clonal T-Cell Disease From Felty Syndrome to Terminal Aggressive Progression

An autopsy-confirmed case reveals shared STAT3 and TET2 mutations linking Felty syndrome to terminal aggressive clonal T-cell ...
Harvard Medical School

Rare Inherited Genetic Mutation Is One of Strongest Indicators Yet for Lung Cancer Risk

C EGFR T790M gene variant face roughly 25 times the lung cancer risk of noncarriers, according to the largest-yet study of the variant. People with ance ...
Newswise

Large-scale study advances detection of DNA mutations across the human genome

Researchers in a Mayo Clinic-led study have shown how to detect a broad range of DNA mutations in noncancerous human tissues ...
Forbes

Rare Genetic Mutation Linked To 25-Fold Higher Lung Cancer Risk

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. A rare, inherited mutation can significantly increase the chances of developing lung cancer, ...

Scientists explore whether humans could live to 194 years by eliminating most causes of ageing, but DNA mutations may still set a biological limit

Scientists estimate that humans could theoretically live 146 to 194 years if most ageing processes were eliminated, but DNA ...
Wired

A Genetic Mutation Is Making It Easier for Drug-Resistant Malaria to Spread

New findings shed light on what’s making the parasite less treatable using the drug that’s considered a first line of defense. The main drug that has been in use for decades to combat malaria in ...
Contagion Live

Candida auris Evades Antifungals Without FKS1 Mutations

Serial Candida auris (C auris) bloodstream isolates from two critically ill patients failed anidulafungin therapy despite carrying no non-synonymous mutations in FKS1 or FKS2, acc ...