Melatonin is one of the most popular sleep aids, but new research suggests it may not be risk-free when taken long term.

Long-term melatonin use among patients with insomnia is associated with negative cardiac effects, new research suggests.

Melatonin is typically considered safe and well-tolerated for short-term use among those who are not pregnant or breastfeeding. That means around 1 to 2 months. There is limited research on the supplement's effects after that time, a situation that some researchers believe should be remedied, especially as the supplement grows in popularity.

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