Listening to a favorite song can trigger a profound emotional response that rivals the feelings produced by biological ...

Chronic pain is a daily reality for millions of Americans, interfering with their everyday activities and quality of life. An ...

A federal bankruptcy court judge on Friday said he will approve OxyContin-maker Purdue Pharma’s latest deal to settle ...

A federal bankruptcy court judge on Friday said he will approve OxyContin-maker Purdue Pharma’s latest deal — which would ...

OxyContin maker Purdue Pharma urged a bankruptcy judge on Wednesday to approve a restructuring plan that includes a $7.4 ...

Scientists have discovered that the body can naturally dull pain through its own localized “benzodiazepine-like” peptides. A groundbreaking study led by a University of Leeds scientist has unveiled ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid ...

The findings of this study confirm that negative reinforcement is a core mechanism in opioid addiction, which is well established in preclinical research but less represented in treatment. Importantly ...

Utilizing high-quality, time-series Quantitative Trait Loci (QTL) mapping, the work provides compelling evidential support for novel, time-dependent genetic interactions (epistasis). A fundamental ...

The treatment of pain in the United States is a major public health issue. Our current treatments are inadequate, and the consequences are deadly. A key strategy must be safe and effective non-opioid ...

In a first, scientists used cryo-electron microscopy to visualize how opioids and the antidote naloxone (Narcan) engage the ...