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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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A new study is raising the possibility that GLP-1 medications could do more than help with weight loss and blood sugar control - they may also influence how the body ages. Researchers found that older female mice treated with semaglutide, the drug behind Ozempic and Wegovy, lived a median of 834 days compared with 742 days for untreated mice - about 12% longer. The treated mice also showed better physical function and fewer biological signs linked to aging, including inflammation and cellular de
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Understanding Metoprolol: a beta blocker that slows heart rate and lowers blood pressure. Important for nursing students to know its uses and precautions, especially for asthmatics and diabetics. What are your experiences with this medication? #Metoprolol #BetaBlocker #NursingSchool #CardiacNursing #RNStudent
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